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KMID : 0911820130140020058
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Korean Journal of Headache
2013 Volume.14 No. 2 p.58 ~ p.62
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Clinical Characteristics of Migraine Subjects with Nausea and Vomiting: An Analysis of Data from the Korean Headache Survey
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Kim Byung-Su
Chung Chin-Sang
Lee Chung-Bin
Chu Min-Kyung
Kim Byung-Kun
Kim Jae-Moon
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Abstract
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Backgrounds: Although nausea and vomiting are common symptoms of migraine, their relationship with other clinical characteristics has been rarely reported, particularly in Asian population. Therefore, we studied the association of clinical characteristics with nausea and vomiting in the Korean migraine subjects.
Methods: We analyzed the data from the Korean Headache Survey designed to identify primary headache disorders using the ICHD-2 criteria in Korean population aged 19-65. Socioeconomic profiles (age, gender, geographical region, education level, and BMI) and clinical characteristics (headache intensity [visual analogue scale, VAS; 0-10], monthly frequency, location, pain quality, worsening by routine activity, nausea, vomiting, photophobia, phonophobia, and osmophobia) were collected using a 29-item, semi-structured interview. Migraine subjects were dichotomically divided according to the presence of migraine-related nausea and/or vomiting. Logistic regression analysis was used to identify clinical characteristics associated with nausea and vomiting.
Results: Of 1507 study subjects, 91 (6.0%) met the migraine criteria of ICHD-2; 57 (62.6%) reported migraine-related nausea and/or vomiting. Socioeconomic profile did not differ between migraine subjects with and without nausea and vomiting. After adjustment of socioeconomic covariates, VAS score (OR: 1.34, 95% CI: 1.02-1.75) and osmophobia (OR: 2.92, 95% CI: 1.13-7.54) were associated with nausea and vomiting.
Conclusions: This is the first epidemiological study that analyzed clinical significance of nausea and vomiting in the Korean migraine population. The study showed that headache intensity and osmophobia were independently associated with migraine-related nausea and vomiting.
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KEYWORD
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Headache, Migraine, Nausea, Vomiting
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